IBRANCE® IS THE FIRST FDA-APPROVED MEDICATION in its class. IBRANCE is a targeted therapy known as a CDK 4/6 inhibitor. It is not a traditional chemotherapy. Taken in combination with certain hormonal therapies, IBRANCE works to put the brakes on cell growth in both healthy and cancer cells. This helps slow the progression of cancer, but it can also cause side effects, some of which are serious.
IBRANCE is for hormone receptor positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (mBC)—breast cancer that has spread to other parts of the body—or HR+/HER2- mBC.
Hormone receptor positive includes both estrogen receptor positive (ER+) and/or progesterone receptor positive (PR+) subtypes. If your subtype is ER+ and/or PR+, you’re more likely to respond to hormone therapies, like an aromatase inhibitor or fulvestrant, that reduce the effects of hormones.
If your subtype is HER2-, your cancer cells have less HER2 protein expression and, therefore, are less likely to respond to anti-HER2 therapies.
HR+, HER2- is the most common subtype of metastatic breast cancer, representing approximately 60% of all cases.
IBRANCE combination therapy was studied in 2 different clinical trials. Whether you’ve previously received hormonal therapy for your metastatic disease before or not, talk to your healthcare team to learn if IBRANCE is right for you.
IBRANCE is a targeted therapy known as a CDK 4/6 inhibitor. It is not a traditional chemotherapy. IBRANCE works to put the brakes on cell growth in both healthy and cancer cells. This helps slow the progression of cancer, but it can also cause side effects, some of which are serious.
IBRANCE is available from Elixi. For more information contact us at info@elixi-int.com
Phone/Fax +41 91 6822040
